A High-Salt Diet Compromises Antibacterial Neutrophil Responses through Hormonal Perturbation.

Jobin K, Stumpf NE, Schwab S, Eichler M, Neubert P, Rauh M, Adamowski M, Babyak O, Hinze D, Sivalingam S, Weisheit C, Hochheiser K, Schmidt SV, Meissner M, Garbi N, Abdullah Z, Wenzel U, Hölzel M, Jantsch J, Kurts C. Sci. Transl. Med. 2020, 12 (536), eaay3850.

PMID: 32213629

Crosstalk between Sentinel and Helper Macrophages Permits Neutrophil Migration into Infected Uroepithelium. 

Schiwon M, Weisheit C, Franken L, Gutweiler S, Dixit A, Meyer-Schwesinger C, Pohl JM, Maurice NJ, Thiebes S, Lorenz K, Quast T, Fuhrmann M, Baumgarten G, Lohse MJ, Opdenakker G, Bernhagen J, Bucala R, Panzer U, Kolanus W, Gröne HJ, Garbi N, Kastenmüller W, Knolle PA, Kurts C*, Engel DR*. Cell 2014, 156 (3), 456–468.
* Authors contributed equally

PMID: 24485454

Exclusive CX3CR1 Dependence of Kidney DCs Impacts Glomerulonephritis Progression.

Hochheiser K, Heuser C, Krause TA, Teteris S, Ilias A, Weisheit C, Hoss F, Tittel AP, Knolle PA, Panzer U, Engel DR, Tharaux PL, Kurts C. J. Clin. Invest. 2013, 123 (10), 4242–4254. 

PMID: 23999431

Alternative Cross-Priming through CCL17-CCR4-Mediated Attraction of CTLs toward NKT Cell–Licensed DCs. 

Semmling V, Lukacs-Kornek V, Thaiss CA, Quast T, Hochheiser K, Panzer U, Rossjohn J, Perlmutter P, Cao J, Godfrey DI,Savage PB, Knolle PA, Kolanus W, Förster I, Kurts C. Nat. Immunol. 2010, 11 (4), 313–320. 

PMID: 20190758

Distinct Pathways of Antigen Uptake and Intracellular Routing in CD4 and CD8 T Cell Activation. 

Burgdorf S, Kautz A, Böhnert V, Knolle PA, Kurts C. Science 2007, 316 (5824), 612–616. 

PMID: 17463291

Determining Individual Glomerular Proteinuria and Periglomerular Infiltration in a Cleared Murine Kidney by a 3-Dimensional Fast Marching Algorithm.

Böhner AMC, Effland A, Jacob AM, Böhner KAM, Abdullah Z, Brähler S, Attenberger UI, Rumpf M, Kurts C.

PMID: 38458475

Increased Type-I Interferon Level Is Associated with Liver Damage and Fibrosis in Primary Sclerosing Cholangitis.

Salzmann RJS, Krötz C, Mocan T, Mocan LP, Grapa C, Rottmann S, Reichelt R, Keller CM, Langhans B, Schünemann F, Pohl A, Böhler T, Bersiner K, Krawczyk M, Milkiewicz P, Sparchez Z, Lammert F, Gehlert S, Gonzalez-Carmona M A, Willms A, Strassburg CP, Kornek MT, Dold L, Lukacs-Kornek V. 

PMID: 38358371

Rapid Protection against Viral Infections by Chemokine-Accelerated Post-Exposure Vaccination. 

Heine A, Lemmermann NAW, Flores C, Becker-Gotot J, Garbi N, Brossart P, Kurts C.

PMID: 38348028

Conditional NKT Cell Depletion in Mice Reveals a Negative Feedback Loop That Regulates CTL Cross-Priming.

Heuser-Loy C, Baumgart AK, Hackstein CP, Courrèges CJF, Philipp MS, Thaiss CA, Holland T, Evaristo C, Garbi N, Kurts C. J. Immunol. 2023, ji2300662. https://doi.org/10.4049/jimmunol.2300662.

PMID: 38019126

Mucosal-Associated Invariant T Cells Contribute to Suppression of Inflammatory Myeloid Cells in Immune-Mediated Kidney Disease.

Gnirck AC, Philipp MS, Waterhölter A, Wunderlich M, Shaikh N, Adamiak V, Henneken L, Kautz T, Xiong T, Klaus D, Tomczyk P, Al-Bahra MM, Menche D, Walkenhorst M, Lantz O, Willing A, Friese MA, Huber TB, Krebs CF, Panzer U, Kurts C, Turner JE. Nat. Commun. 2023, 14 (1), 7372. https://doi.org/10.1038/s41467-023-43269-0

PMID: 37968302

The Endosomal System of Primary Human Vascular Endothelial Cells and Albumin–FcRn Trafficking. 

Pannek A, Becker-Gotot J, Dower SK, Verhagen AM, Gleeson PA. J. Cell Sci. 2023, 136 (15), jcs260912. https://doi.org/10.1242/jcs.260912.

PMID: 37565427

Fate Mapping Reveals Compartment-Specific Clonal Expansion of Mononuclear Phagocytes during Kidney Disease

Yin J, Mei Q, Prinz M, Abdullah Z, Panzer U, Li J, Von Vietinghoff S, Kurts C. Kidney Int. 2023, S0085253823004015. https://doi.org/10.1016/j.kint.2023.04.031.

PMID: 37290602

Cigarette Smoke Depletes Alveolar Macrophages and Delays Clearance of Legionella Pneumophila. 

Fleischmann M, Jarnicki AG, Brown AS, Yang C, Anderson GP, Garbi N, Hartland EL, van Driel IR, Ng GZ. Am. J. Physiol. Lung Cell. Mol. Physiol. 2023. https://doi.org/10.1152/ajplung.00268.2022.

PMID: 36719079

Potentially Improved Response of COVID-19 Vaccinated Nasopharyngeal Cancer Patients to Combination Therapy with Anti-PD-1 Blockade and Chemotherapy.
Hua Y J, Liu YL, Wen K, Kurts C, Wu H, Mei Q, Li J. Ann. Oncol. 2022, S0923753422041886. https://doi.org/10.1016/j.annonc.2022.10.002

PMID: 36216192

Immune Tolerance against Infused FVIII in Hemophilia A Is Mediated by PD-L1+ Regulatory T Cells.
Becker-Gotot J,  Meissner M, Kotov V, Jurado-Mestre B, Maione A, Pannek A, Albert T, Flores C, Schildberg FA, Gleeson PA, Reipert BM, Oldenburg J, Kurts C. J. Clin. Invest. 2022 https://doi.org/10.1172/JCI159925.
PMID: 36107620

Monocyte-Derived Macrophages Aggravate Pulmonary Vasculitis via CGAS/STING/IFN-Mediated Nucleic Acid Sensing. 

Kessler N, Viehmann SF, Krollmann C, Mai K, Kirschner KM, Luksch H, Kotagiri P, Böhner AMC, Huugen D, de Oliveira Mann CC, Otten S, Weiss SAI, Zillinger T, Dobrikova K, Jenne DE, Behrendt R, Ablasser A, Bartok E, Hartmann G, Hopfner KP, Lyons PA, Boor P, Rösen-Wolff A, Teichmann LL, Heeringa P, Kurts C, Garbi N. J. Exp. Med. 2022, 219 (10), e20220759.

PMID: 35997679

Generation of an Alpaca Serum That Induces Immune-Mediated Crescentic Glomerulonephritis in Mice.

Dhana E, Klaus D, Böhner A, Schmidt F, von Vietinghoff S, Boor P, Djudjaj S, Kurts C. J. Immunol. Methods 2022, 507, 113310

PMID: 35787393

Impact of COVID-19 vaccination on the use of PD-1 inhibitor in treating patients with cancer: a real-world study

Mei Q, Hu G, Yang Y,  Liu B, Yin J, Li M, Huang Q, Tang X, Böhner A, Bryant A, Kurts C, Yuan X, Li, J. J Immunother Cancer 2022 Mar;10(3):e004157.

PMID: 35264438

Health Issues and Immunological Assessment Related to Wuhan’s COVID-19 Survivors: A Multicenter Follow-Up Study. 

Mei Q, Wang F, Yang Y,  Hu G, Guo S, Zhang Q, Bryant A, Zhang L, Kurts C, Wei L, Yuan X, Li, J. Front. Med. 2021, 8, 617689. 

PMID: 34026775

Regulation and Function of CX3CR1 and Its Ligand CX3CL1 in Kidney Disease.

von Vietinghoff S, Kurts C. 

PMID: 34009468

Sodium and Its Manifold Impact on Our Immune System. 

Jobin K, Müller DN, Jantsch J, Kurts C. Trends Immunol. 2021, 42 (6), 469–479. 

PMID: 33962888

Survival Factors and Metabolic Pathogenesis in Elderly Patients (≥65) With COVID-19: A Multi-Center Study. 

Mei Q, Wang AY, Bryant A, Yang Y, Li M, Wang F, Du S, Kurts C, Wu P, Ma K, Wu L, Chen H, Luo J, Li Y, Hu G, Yuan X, Li J. Front. Med. 2021, 7, 595503.

PMID: 33585504

Vascular Pathologies in Chronic Kidney Disease: Pathophysiological Mechanisms and Novel Therapeutic Approaches.

Düsing P, Zietzer A, Goody PR, Hosen MR, Kurts C, Nickenig G, Jansen F. J. Mol. Med. 2021, 99 (3), 335–348. 

PMID: 33481059

A High-Salt Diet Compromises Antibacterial Neutrophil Responses through Hormonal Perturbation.

Jobin K, Stumpf NE, Schwab S, Eichler M, Neubert P, Rauh M, Adamowski M, Babyak O, Hinze D, Sivalingam S, Weisheit C, Hochheiser K, Schmidt SV, Meissner M, Garbi N, Abdullah Z, Wenzel U, Hölzel M, Jantsch J, Kurts C. Sci. Transl. Med. 2020, 12 (536), eaay3850.

PMID: 32213629

Splenic Red Pulp Macrophages Cross-Prime Early Effector CTL That Provide Rapid Defense against Viral Infections.

Enders M, Franken L, Philipp MS, Kessler N, Baumgart AK, Eichler M, Wiertz EJH, Garbi N, Kurts C. J. Immunol. 2020, 204 (1), 87–100. 

PMID: 31776205

Development and Validation of Prognostic Model for Predicting Mortality of COVID-19 Patients in Wuhan, China.

Mei Q, Wang AY, Bryant A, Yang Y, Li M, Wang F, Zhao JW, Ma K, Wu L, Chen H, Luo J, Du S, Halfter K, Li Y, Kurts C, Hu G, Yuan X, Li J. Sci. Rep. 2020, 10 (1), 22451

PMID: 33384422

Pathogen-Induced Tissue-Resident Memory TH17 (TRM17) Cells Amplify Autoimmune Kidney Disease.

Krebs CF, Reimers D, Zhao Y, Paust HJ, Bartsch P, Nuñez S, Rosemblatt MV, Hellmig M, Kilian C, Borchers A, Enk LUB, Zinke M, Becker M, Schmid J, Klinge S, Wong MN, Puelles VG, Schmidt C, Bertram T, Stumpf N, Hoxha E, Meyer-Schwesinger C, Lindenmeyer MT, Cohen CD, Rink M, Kurts C, Franzenburg S, Koch-Nolte F, Turner JE, Riedel JH, Huber S, Gagliani N, Huber TB, Wiech T, Rohde H, Bono MR, Bonn S, Panzer U, Mittrücker HW. Sci. Immunol. 2020, 5 (50).

PMID: 32769171

NCX1 Represents an Ionic Na+ Sensing Mechanism in Macrophages. 

Neubert P, Homann A, Wendelborn D, Bär AL, Krampert L, Trum M, Schröder A, Ebner S, Weichselbaum A, Schatz V, Linz P, Veelken R, Schulte-Schrepping J, Aschenbrenner AC, Quast T, Kurts C, Geisberger S, Kunzelmann K, Hammer K, Binger KJ, Titze J, Müller DN, Kolanus W, Schultze JL, Wagner S, Jantsch J. PLoS Biol. 2020, 18 (6), e3000722.

PMID: 32569301